Test Code SUPRA Supersaturation Profile, Random, Urine
Ordering Guidance
A timed 24-hour urine collection is the preferred specimen for measuring and interpreting this profile to determine kidney stone risk factors (SUP24 / Supersaturation Profile, 24 Hour, Urine). Random urine collections with individual analytes normalized to urinary creatinine may be of some clinical use in patients who cannot collect a 24-hour specimen, typically small children. Therefore, this test is offered on random collections for children less than 16 years old.
X-ray dyes and contrast media will affect uric acid test results.
-If a kidney X-ray with dye or computerized tomography (CT) scan with contrast has been performed, patient should wait a minimum of 1 day before starting collection.
-If a cholangiography (bile duct X-ray) has performed, patient should wait 7 days before starting collection.
-Urine must be collected before tablets have been taken for gallbladder X-ray, otherwise patient should wait 7 days before starting collection.
Necessary Information
Patient's age is required.
Specimen Required
Supplies:
-Urine Tubes, 10 mL (T068)
-Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: 90 mL urine container
Submission Container/Tube: 2 x 10 mL plastic urine tubes and 5 x 5 mL plastic urine tubes
Specimen Volume: 40 mL
Collection Instructions:
1. Collect a random urine specimen, mix collection container thoroughly and divide the urine into 7 plastic tubes (2 x 10 mL and 5 x 5 mL).
2. Refrigerate specimen after collection. Specimen pH should be between 4.5 and 8 and will stay in this range if kept refrigerated. Specimens with pH above 8 indicate bacterial contamination, and testing will be canceled. Do not attempt to adjust pH as it will adversely affect results.
Secondary ID
616375Useful For
Diagnosis and management of patients with renal lithiasis:
-Predicting the likely composition of the stone, in patients who have a radiopaque stone, for whom stone analysis is not available which may help in designing a treatment program
-Identifying specific risk factors for stones formation using a random urine collection
-Monitoring the effectiveness of therapy by confirming that the crystallization potential has indeed decreased
-Evaluation of kidney excretion of acid and urine pH
Profile Information
Test ID | Reporting Name | Available Separately | Always Performed |
---|---|---|---|
SRINT | Supersaturation, Random, U 1 | No | Yes |
RANAU | Sodium, Random, U | Yes, (order RNAUR) | Yes |
RAKUR | Potassium, Random, U | Yes, (order RKUR) | Yes |
RACAL | Calcium, Random, U | Yes, (order CACR3) | Yes |
RAMAG | Magnesium, Random, U | Yes, (order MAGRU) | Yes |
RACLU | Chloride, Random, U | Yes, (order RCHLU) | Yes |
RAPOU | Phosphorus, Random, U | Yes, (order RPHOC) | Yes |
RASUL | Sulfate, Random, U | No | Yes |
RACIT | Citrate Excretion, Random, U | Yes, (order CITRA) | Yes |
RAOXU | Oxalate, Random, U | Yes, (order ROXUR) | Yes |
RAPHU | pH, Random, U | No | Yes |
RAURA | Uric Acid, Random, U | Yes, (order RURC1) | Yes |
RACTU | Creatinine, Random, U | Yes, (order RCTUR) | Yes |
RAOSM | Osmolality, Random, U | No | Yes |
RAAMM | Ammonium, Random, U | Yes, (order RAMBO) | Yes |
Method Name
RACIT, RAAMM, RAOXU: Enzymatic
RAOSM: Freezing Point Depression
RASUL: High-Performance Ion Chromatography (HPIC)
RAMAG: Colorimetric Endpoint Assay
RACAL, RAPOU: Photometric
RAPHU: pH Meter
RANAU, RAKUR, RACLU: Potentiometric, Indirect Ion-Selective Electrode (ISE)
RACTU: Enzymatic Colorimetric Assay
RAURA: Uricase
Reporting Name
Supersaturation, Random, USpecimen Type
UrineSpecimen Minimum Volume
30 mL
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
Urine | Refrigerated (preferred) | 14 days |
Frozen | 14 days | |
Ambient | 72 hours |
Reject Due To
pH <4.5 or >8.0 | Reject |
Reference Values
The following analytes do not have any established reference values:
Sodium, potassium, chloride, phosphorus, citrate, sulfate, and oxalate
pH: 4.5-8.0
CREATININE
≥18 years old: 16-326 mg/dL
Reference values have not been established for patients who are younger than 18 years.
OSMOLALITY
0-11 months: 50-750 mOsm/kg
≥12 months: 150-1,150 mOsm/kg
AMMONIUM
18-77 years: 3-65 mmol/L
No reference values established for patients who are younger than 18 years or older than 77 years.
CALCIUM
1 month-<12 months: 0.03-0.81 mg/mg creat
12 months-<24 months: 0.03-0.56 mg/mg creat
24 months-<3 years: 0.02-0.50 mg/mg creat
3 years-<5 years: 0.02-0.41 mg/mg creat
5 years-<7 years: 0.01-0.30 mg/mg creat
7 years-<10 years: 0.01-0.25 mg/mg creat
10 years-<18 years: 0.01-0.24 mg/mg creat
18 years-83 years: 0.05-0.27 mg/mg creat
Reference values have not been established for patients who are younger than 1 month or older than 83 years.
MAGNESIUM
Magnesium/Creatinine Ratio:
1 month-<12 months: 0.10-0.48 mg/mg creat
12 months-<24 months: 0.09-0.37 mg/mg creat
24 months-<3 years: 0.07-0.34 mg/mg creat
3 years-<5 years: 0.07-0.29 mg/mg creat
5 years-<7 years: 0.06-0.21 mg/mg creat
7 years-<10 years: 0.05-0.18 mg/mg creat
10 years-<14 years: 0.05-0.15 mg/mg creat
14 years-<18 years: 0.05-0.13 mg/mg creat
18 years-83 years: 0.04-0.12 mg/mg creat
Reference values have not been established for patients who are younger than 1 month or older than 83 years.
Day(s) Performed
Monday through Sunday
Report Available
2 to 5 daysPerforming Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82310-Calcium
82436-Chloride
82507-Citrate excretion
82570-Creatinine
83735-Magnesium
83935-Osmolality
83945-Oxalate
83986-pH
84105-Phosphorus
84133-Potassium
84300-Sodium
84392-Sulfate
84560-Uric acid
82140-Ammonium
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
SUPRA | Supersaturation, Random, U | 101929-8 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
RASUC | Sulfate, Random, U | 2975-1 |
RAPHU | pH, Random, U | 2756-5 |
RAOSU | Osmolality, Random, U | 2695-5 |
RANAC | Sodium, Random, U | 2955-3 |
RACTU | Creatinine, Random, U | 2161-8 |
RAKUC | Potassium, Random, U | 2828-2 |
RACLC | Chloride, Random, U | 2078-4 |
RAAMM | Ammonium, Random, U | 1842-4 |
RACAC | Calcium, Random, U | 17862-4 |
CITCO | Citrate Excretion, Random, U | 2128-7 |
RAMGC | Magnesium, Random, U | 19124-7 |
POUCO | Phosphorus, Random, U | 2778-9 |
RAUAC | Uric Acid, Random, U | 3086-6 |
OXMCO | Oxalate, Random, U (mmol/L) | 15086-2 |
616399 | Calcium Oxalate Crystal | In Process |
616400 | Brushite Crystal | In Process |
OXGCO | Oxalate, Random, U (mg/L) | 2700-3 |
UACCR | Uric Acid/Creat Ratio, Random, U | 3089-0 |
PHOCR | Phosphorus/Creat Ratio, Random, U | 11141-9 |
MAGCR | Magnesium/Creat Ratio, Random, U | 13474-2 |
CITCR | Citrate/Creatinine Ratio, Random, U | 13722-4 |
CALCR | Calcium/Creatinine Ratio, Random, U | 9321-1 |
OXUCR | Oxalate/Creatinine Ratio, Random, U | 13483-3 |
616401 | Hydroxyapatite Crystal | In Process |
616402 | Uric Acid Crystal | In Process |
31246 | Interpretation | 69051-1 |
Forms
If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.